14
Bronchology Past, Present and Future Diagnostic Procedures
In the 1970s, the U.S. National Cancer Institute sponsored lung cancer screen-
ing trials at three medical centers.
John Hopkins University The John Hopkins Lung Project (JHLP)
Mayo Clinic Mayo Lung Project (MLP)
Memorial Sloan-Kettering Cancer Center (MSKLP)
Similar issues were examined in two additional studies, i. e. the Czechoslovak
trial and the Japanese trials.
Study
Subjects
Eligibility
Group
Cases
Mortality
Detected
Rate
(MLP)
10,933
Male smokers
Prevalence
91
N/A
Mayo Lung
Age >45
Project
4,618
Age >45
Screened
206
3.2
4,593
Age >45
Control
160
3.0
(JHLP)
5,226
Age >45
Screened
194
3.4
John Hopkins
5,161
Age >45
Control
202
3.8
Lung Project
(MSKLP)
5,072
Age >45
Screened
144
2.7
Memorial Sloan-
4,968
Age >45
Control
144
2.7
Kettering Lung
Project
Czechoslovak
6,364
Male smokers
Prevalence
19
N/A
Trial
Age >40
3,172
Screened
108
3.6
3,174
Control
82
2.6
Study
Radiology
Sputum Cytology
(MLP)
4-monthly
4-monthly
Mayo Lung
Project
(JHLP)
Yearly
Yearly
John Hopkins
Lung Project
(MSKLP)
Yearly
Yearly
Memorial Sloan-
Kettering Lung
Project
Czechoslovak
6-monthly
6-monthly
Trial
Prospective Screening
Trials for Lung Cancer
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